Human recombinant OGG1 (8-oxoguanine DNA glycosylase) protein, AF

8-oxoguanine DNA glycosylase-1 (OGG1) is a major DNA glycosylase that plays a critical role in n base-excision repair (BER) of oxidative DNA damage to nuclear and mitochondrial DNA (mtDNA) to remove 7,8-dihydro-8-oxo-2′-deoxyguanosine (8-OH-dG) . OGG1 is a 38.8 kDa protein containing 52 amino acid it found in bacterial, archaeal and eukaryotic species. OGG1 in DNA causes G:C to T:A transversions and, therefore, it could be responsible for mutations that lead to carcinogenesis.