Anti-CACNB4 Antibody
Boster Bio Anti-CACNB4 Antibody catalog # A06596-2. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE), juvenile myoclonic epilepsy (JME), and episodic ataxia, type 5.
Synonyms
CAB4; CACNB4; CACNLB4; EA5; EJM
Gene Name
CACNB4
UniProt
O00305
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human CACNB4 recombinant protein (Position: S3-K347) .
Clonality
Polyclonal
Applications
WB, IHC
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Gene Name Synonym
Calcium voltage-gated channel auxiliary subunit beta 4
Protein Name
Voltage-dependent L-type calcium channel subunit beta-4
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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