Mouse PVRIG Protein, Mouse IgG2a Fc Tag (MALS verified)

Mouse PVRIG, Mouse IgG2a Fc Tag (PVG-M5253) is expressed from human 293 cells (HEK293) . It contains AA Ser 35 - Asp 165 (Accession # A0A1B0GS01-1) .

Product Specifications

Background

Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.

Specifications

This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 41.0 kDa. The protein migrates as 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

A0A1B0GS01-1

Expression Region

Ser 35 - Asp 165

Host

HEK293

Target

PVRIG

Conjugation

Unconjugated

Tag

C-mFc (mIgG2a)

Source

Mouse

Stability

● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.