Human recombinant HGF protein, AF
Hepatocyte Growth Factor (HGF) activates c-Met receptor's tyrosine kinase cascade, influencing cell growth and motility. Originating from mesenchymal cells, HGF is a multifunctional cytokine that plays a central role in angiogenesis, tumorigenesis, and tissue regeneration. Initially secreted as an inactive polypeptide, HGF undergoes cleavage to become an active heterodimeric molecule. The gene exhibits alternative splicing, resulting in diverse isoforms.
Product Specifications
Synonyms
Hepatocyte growth factor, Hepatopoietin-A, Scatter factor (SF), HPTA
Gene Name
HGF
UniProt
P14210
Reactivity
Human
Tag
His Tag (C-term)
Source
HEK293 cell
Applications
Cell Culture
Purification
>90% as determined by SDS-PAGE.
Endotoxin
<1 EU per 1 μg of the protein by the LAL method.
Bioactivity
Testing in process
Form
Reconstitution
Molecular Weight
The protein has a calculated MW of 80.48 kDa. The protein migrates as 75-100 kDa under reducing condition (SDS-PAGE analysis) .
Storage Conditions
AA Sequence
A DNA sequence encoding Human HGF Protein (#P14210) (Gln 32-Ser 728) was expressed with polyhistidine tag at the C-terminus.
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