Human recombinant TGF beta 1 (Transforming growth factor beta 1) protein, AF
The transforming Growth Factors beta (TGF beta) family of cytokines are ubiquitous, multifunctional, and essential to survival. They play the central roles in growth, development, inflammation, repair, and host immunity. The mammalian TGF beta isoforms (TGF beta 1, beta 2 and beta 3) are secreted as potential precursors and possess a variety of cell surface receptors and produces at least two mediate signal transductions.
Product Specifications
Synonyms
Differentiation inhibiting factor, Cartilage-inducing factor, CED, DPD1, IBDIMDE, LAP, TGFB
Gene Name
TGFB1
UniProt
P01137
Reactivity
Human
Tag
His Tag (N-term)
Source
HEK293 cell
Applications
Cell Culture
Purification
>95% as determined by SDS-PAGE.
Endotoxin
<0.1 EU per 1 μg of the protein by the LAL method.
Bioactivity
Measure by its ability to inhibit the IL-4 dependent proliferation in TF-1 cells. The ED50 for this effect is < 0.1 ng/mL.
Form
The protein was lyophilized from a 0.2 μm filtered solution of PBS, pH 7.0. If you have any concerns or special requirements, please confirm with us.
Reconstitution
Molecular Weight
Storage Conditions
AA Sequence
A DNA sequence encoding Human CD28 ECD (# P01137) (Met1-Ser390) was expressed with polyhistidine tag at the N-terminus.
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