Human recombinant OGG1 (8-oxoguanine DNA glycosylase) protein, AF
Selected Variant
PROTO15527-2-20ug
Size: 20 µg
8-oxoguanine DNA glycosylase-1 (OGG1) is a major DNA glycosylase that plays a critical role in n base-excision repair (BER) of oxidative DNA damage to nuclear and mitochondrial DNA (mtDNA) to remove 7,8-dihydro-8-oxo-2′-deoxyguanosine (8-OH-dG) . OGG1 is a 38.8 kDa protein containing 52 amino acid it found in bacterial, archaeal and eukaryotic species. OGG1 in DNA causes G:C to T:A transversions and, therefore, it could be responsible for mutations that lead to carcinogenesis.
Product Specifications
Synonyms
HMMH, MUTM, OGH1, HOGG1
Gene Name
OGG1
UniProt
O15527
Reactivity
Human
Tag
His Tag (C-term)
Source
Escherichia coli
Applications
Cell Culture
Purification
>98% as determined by SDS-PAGE.
Endotoxin
<0.1 EU per 1 μg of the protein by the LAL method.
Bioactivity
Testing in process
Form
Reconstitution
Molecular Weight
The protein has a calculated MW of 39.61 kDa. The protein migrates as 40 kDa under reducing condition (SDS-PAGE analysis) .
Storage Conditions
AA Sequence
Price
Frequently Asked Questions
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