Swine recombinant Flt-3 Ligand (Fms-related tyrosine kinase-3 ligand) protein, AF
Selected Variant
PROTD2K7D6-5ug
Size: 5 µg
Fms-related tyrosine kinase-3 ligand (Flt-3 Ligand) is a protein as an important regulator of hematopoiesis, Flt-3 ligand has a tyrosine-protein kinase activity that stimulate the proliferation of hematopoietic progenitor cells of both lymphoid and myeloid origin. Flt-3 ligand can synergistically increase the proliferation of immature progenitors with other cytokines such as GM-CSF, G-CSF, IL-3, EPO, IL-11, IL-12, IL-6 or TPO. Flt-3 ligand is expressed by a variety of hematopoietic progenitor cells including immature hematopoietic and marrow stromal cells.
Product Specifications
Synonyms
Flt3l, FLT3LG
Gene Name
IGF1
UniProt
D2K7D6
Reactivity
Swine
Tag
His Tag (C-term)
Source
Escherichia coli
Applications
Cell Culture
Purification
>95% as determined by SDS-PAGE.
Endotoxin
<0.1 EU per 1 μg of the protein by the LAL method.
Bioactivity
Measure by its ability to induce proliferation in OCI-AML5 cells. The ED50 for this effect is <5 ng/mL.
Form
Reconstitution
Molecular Weight
The protein has a calculated MW of 20.4 kDa. The protein migrates as 17 kDa under reducing condition (SDS-PAGE analysis) .
Storage Conditions
AA Sequence
Price
Frequently Asked Questions
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