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Anti-CERS4 Antibody (N-Term)

Boster Bio Anti-CERS4 Antibody (N-Term) (Catalog # M30561) . Tested in WB, Flow Cytometry application (s) . This antibody reacts with Human.

Product Specifications

Background

May be either a bona fide (dihydro) ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner (By similarity) .

Synonyms

Ceramide synthase 4, CerS4, LAG1 longevity assurance homolog 4, CERS4, LASS4

Gene Name

CERS4

UniProt

Q9HA82

Host

Rabbit

Reactivity

Human

Immunogen

This CERS4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 21-51 amino acids from human CERS4.

Clonality

Polyclonal

Applications

WB, Flow Cytometry

Field of Research

Cancer, Metabolism, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward long and very-long chains (C18:0-C22:0) as acyl donor.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

46399 Da

Subcellular Location

Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9D6J1}; Multi-pass membrane protein

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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