Anti-CCRK Antibody (N-term)
Boster Bio Anti-CCRK Antibody (N-term) (Catalog # M13734) . Tested in WB application (s) . This antibody reacts with Human.
Product Specifications
Background
Required for high-level Shh responses in the developing neural tube. Together with BROMI, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity) . Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'.
Synonyms
Cyclin-dependent kinase 20, CDK-activating kinase p42, CAK-kinase p42, Cell cycle-related kinase, Cell division protein kinase 20, Cyclin-dependent protein kinase H, Cyclin-kinase-activating kinase p42, CDK20, CCRK, CDCH
Gene Name
CDK20
UniProt
Q8IZL9
Host
Mouse
Reactivity
Human
Immunogen
Purified His-tagged CCRK protein was used to produced this monoclonal antibody.
Clonality
Monoclonal
Clone
Clone: 885CT27.1.1
Applications
WB
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Function
Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity) . Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
38695 Da
Applications Notes
WB: 1:1000
Subcellular Location
Nucleus. Cytoplasm. Cell projection, cilium
Isotype
IgG1
Contents
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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