Anti-DMRT2 Antibody (Center)
Boster Bio Anti-DMRT2 Antibody (Center) (Catalog # M10308) . Tested in WB application (s) . This antibody reacts with Human.
Product Specifications
Background
Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity) .
Synonyms
Doublesex- and mab-3-related transcription factor 2, Doublesex-like 2 protein, DSXL-2, DMRT2, DSXL2
Gene Name
DMRT2
UniProt
Q9Y5R5
Host
Rabbit
Reactivity
Human
Immunogen
This DMRT2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 357-392 amino acids from the Central region of human DMRT2.
Clonality
Polyclonal
Tissue Specificity
Expressed in testis, kidney and skeletal muscle.
Applications
WB
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity) .
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
61814 Da
Applications Notes
WB: 1:2000
Subcellular Location
Nucleus {ECO:0000255|PROSITE-ProRule:PRU00070}.
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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