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Anti-DMRT2 Antibody (Center)

Boster Bio Anti-DMRT2 Antibody (Center) (Catalog # M10308) . Tested in WB application (s) . This antibody reacts with Human.

Product Specifications

Background

Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity) .

Synonyms

Doublesex- and mab-3-related transcription factor 2, Doublesex-like 2 protein, DSXL-2, DMRT2, DSXL2

Gene Name

DMRT2

UniProt

Q9Y5R5

Host

Rabbit

Reactivity

Human

Immunogen

This DMRT2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 357-392 amino acids from the Central region of human DMRT2.

Clonality

Polyclonal

Tissue Specificity

Expressed in testis, kidney and skeletal muscle.

Applications

WB

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity) .

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

61814 Da

Applications Notes

WB: 1:2000

Subcellular Location

Nucleus {ECO:0000255|PROSITE-ProRule:PRU00070}.

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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