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Anti-FAM120A Antibody

Boster Bio Anti-FAM120A Antibody (Catalog # M09208) . Tested in WB, IHC-P, IF application (s) . This antibody reacts with Human.

Product Specifications

Background

May participate in mRNA transport in the cytoplasm (By similarity) . Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous- type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.

Synonyms

Constitutive coactivator of PPAR-gamma-like protein 1, Oxidative stress-associated Src activator, Protein FAM120A, FAM120A, C9orf10, KIAA0183, OSSA

Gene Name

FAM120A

UniProt

Q9NZB2

Host

Mouse

Reactivity

Human

Immunogen

This FAM120A antibody is generated from a mouse immunized with a recombinant protein of human FAM120A.

Clonality

Monoclonal

Clone

Clone: 1501CT803.19.85.5

Tissue Specificity

Widely expressed (PubMed:14585507) . In gastric mucosa, detected in the bottom region of the foveolar epithelium (at protein level) (PubMed:19015244) .

Applications

WB, IHC-P, IF

Field of Research

Cell Biology, Signal Transduction

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

190152441901524419015244

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

121888 Da

Subcellular Location

Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Translocates from the cytosol to plasma membrane after UV irradiation.

Isotype

IgG1, k

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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