Anti-ALDH6A1 Antibody
Boster Bio Anti-ALDH6A1 Antibody (Catalog # M08868) . Tested in WB, IF, IHC-P application (s) . This antibody reacts with Human.
Product Specifications
Background
This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
Synonyms
Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial, MMSDH, Malonate-semialdehyde dehydrogenase [acylating], Aldehyde dehydrogenase family 6 member A1, ALDH6A1, MMSDH
Gene Name
ALDH6A1
UniProt
Q02252
Host
Mouse
Reactivity
Human
Immunogen
This ALDH6A1 antibody is generated from mouse immunized with ALDH6A1 recombinant protein.
Clonality
Monoclonal
Clone
Clone: 147CT8.3.4
Applications
WB, IF, IHC-P
Field of Research
Metabolism, Signal Transduction, Mitochondria
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Function
Malonate and methylmalonate semialdehyde dehydrogenase involved in the catabolism of valine, thymine, and compounds catabolized by way of beta-alanine, including uracil and cytidine.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
57840 Da
Subcellular Location
Mitochondrion.
Isotype
IgG1, IgK
Contents
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
