Anti-KCNMB2 Antibody (N-term)
Boster Bio Anti-KCNMB2 Antibody (N-term) (Catalog # M08181) . Tested in WB application (s) . This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons.
Synonyms
Calcium-activated potassium channel subunit beta-2, BK channel subunit beta-2, BKbeta2, Hbeta2, Calcium-activated potassium channel, subfamily M subunit beta-2, Charybdotoxin receptor subunit beta-2, Hbeta3, K (VCA) beta-2, Maxi K channel subunit beta-2, Slo-beta-2, KCNMB2
Gene Name
KCNMB2
UniProt
Q9Y691
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
This KCNMB2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-66 amino acids from the N-terminal region of human KCNMB2.
Clonality
Polyclonal
Tissue Specificity
Expressed in kidney, heart and brain. Highly expressed in ovary. Expressed at low level in other tissues
Applications
WB
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
27130 Da
Applications Notes
WB: 1:2000
Subcellular Location
Membrane; Multi-pass membrane protein.
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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