Anti-NSFL1C Antibody (Center)
Boster Bio Anti-NSFL1C Antibody (Center) (Catalog # M08116) . Tested in WB, IHC-P, Flow Cytometry application (s) . This antibody reacts with Human, Mouse.
Product Specifications
Background
Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER) (By similarity) . Inhibits the activity of CTSL (in vitro) .
Synonyms
NSFL1 cofactor p47, UBX domain-containing protein 2C, p97 cofactor p47, NSFL1C, UBXN2C
Gene Name
NSFL1C
UniProt
Q9UNZ2
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This NSFL1C antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 214-248 amino acids from the Central region of human NSFL1C.
Clonality
Polyclonal
Applications
WB, IHC-P, Flow Cytometry
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
154985632364980723649807
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
40573 Da
Subcellular Location
Nucleus {ECO:0000250|UniProtKB:O35987}. Golgi apparatus, Golgi stack {ECO:0000250|UniProtKB:O35987}. Chromosome {ECO:0000250|UniProtKB:O35987}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:O35987} Note=Predominantly nuclear in interphase cells. Bound to the axial elements of sex chromosomes in pachytene spermatocytes. A small proportion of the protein is cytoplasmic, associated with Golgi stacks Localizes to centrosome during mitotic prophase and metaphase {ECO:0000250|UniProtKB:O35987}
Prediction Reactivity
Bovine, Rat
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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