Anti-TWF1 Antibody (Center)
Boster Bio Anti-TWF1 Antibody (Center) (Catalog # M07004) . Tested in WB application (s) . This antibody reacts with Human.
Product Specifications
Background
Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles (By similarity) .
Synonyms
Twinfilin-1, Protein A6, Protein tyrosine kinase 9, TWF1, PTK9
Gene Name
TWF1
UniProt
Q12792
Host
Rabbit
Reactivity
Human
Immunogen
This TWF1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 137-171 amino acids from the Central region of human TWF1.
Clonality
Polyclonal
Tissue Specificity
Expressed at high levels in the colon, testis, ovary, prostate and lung. Expressed at lower levels in the brain, bladder and heart. Not detected in liver.
Applications
WB
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles (By similarity) .
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
40283 Da
Applications Notes
WB: 1:2000
Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton. Note=Diffuse cytoplasmic localization with perinuclear and G-actin-rich cortical actin structures sublocalization. Also found at membrane ruffles and cell-cell contacts (By similarity) .
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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