Anti-IL-34 Monoclonal Antibody
Boster Bio Anti-IL-34 Monoclonal Antibody catalog # M06903. Tested in WB, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human.
Product Specifications
Synonyms
Interleukin-34; IL-34; IL34; C16orf77
Gene Name
IL34
UniProt
Q6ZMJ4
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant fragment of human IL-34 expressed in E. Coli.
Clonality
Monoclonal
Clone
Clone: 1D12
Tissue Specificity
Detected in the sinusoidal epithelium in the red pulp of spleen (at protein level) . Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon.
Applications
WB, IF, Flow Cytometry, ELISA
Purification
Affinity purification
Concentration
1 mg/mL
Form
Liquid
Function
Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
27482 MW
Gene Name Synonym
Interleukin-34
Subcellular Location
Secreted
Protein Name
Interleukin-34
Isotype
IgG
Contents
Ascitic fluid containing 0.03% sodium azide.
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