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Anti-beta II Tubulin Antibody

Boster Bio Anti-beta II Tubulin Antibody (Catalog # M06868-1) . Tested in WB, Flow Cytometry, IF application (s) . This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity) .

Synonyms

Tubulin beta-2A chain, Tubb2a, Tubb2

Gene Name

Tubb2a

UniProt

Q7TMM9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 14-46 amino acids from human.

Clonality

Polyclonal

Applications

WB, Flow Cytometry, IF

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

49907 Da

Subcellular Location

Cytoplasm, cytoskeleton.

Prediction Reactivity

Chicken, Monkey, Bovine, Xenopus, Pig

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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