Anti-HAND1 Monoclonal Antibody
Boster Bio Anti-HAND1 Monoclonal Antibody catalog # M06496. Tested in WB, ELISA applications. This antibody reacts with Human.
Product Specifications
Synonyms
Heart- and neural crest derivatives-expressed protein 1; Class A basic helix-loop-helix protein 27; bHLHa27; Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1; eHAND; HAND1; BHLHA27, EHAND
Gene Name
HAND1
UniProt
O96004
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant fragment of HAND1 (aa90-190) expressed in E. Coli.
Clonality
Monoclonal
Clone
Clone: 8E7A11 / 8C2F4
Tissue Specificity
Heart.
Applications
WB, ELISA
Purification
Affinity purification
Concentration
1 mg/mL
Form
Liquid
Function
Transcription factor that plays an essential role in both trophoblast-giant cells differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5'- NRTCTG-3' (non-canonical E-box) (By similarity) . .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
23627 MW
Gene Name Synonym
Heart- and neural crest derivatives-expressed protein 1
Subcellular Location
Nucleus, nucleoplasm . Nucleus, nucleolus . Interaction with MDFIC sequesters it into the nucleolus, preventing the transcription factor activity. Phosphorylation by PLK4 disrupts the interaction with MDFIC and releases it from the nucleolus, leading to transcription factor activity (By similarity) . .
Protein Name
Heart- and neural crest derivatives-expressed protein 1
Isotype
IgG
Contents
Ascitic fluid containing 0.03% sodium azide.
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