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Anti-FLOT2 Antibody (C-Term)

Boster Bio Anti-FLOT2 Antibody (C-Term) (Catalog # M06107-1) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

Product Specifications

Background

May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.

Synonyms

Flotillin-2, Epidermal surface antigen, ESA, Membrane component chromosome 17 surface marker 1, FLOT2, ESA1, M17S1

Gene Name

FLOT2

UniProt

Q14254

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This FLOT2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 322-356 amino acids from human FLOT2.

Clonality

Polyclonal

Tissue Specificity

In skin, expressed in epidermis and epidermal appendages but not in dermis. Expressed in all layers of the epidermis except the basal layer. In hair follicles, expressed in the suprabasal layer but not the basal layer. Also expressed in melanoma and carcinoma cell lines, fibroblasts and foreskin melanocytes

Applications

WB

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

47064 Da

Applications Notes

WB: 1:2000

Subcellular Location

Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Endosome Membrane; Lipid-anchor. Note=Membrane- associated protein of caveolae

Prediction Reactivity

Bovine, Rat

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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