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Anti-IMPA1 Antibody

Boster Bio Anti-IMPA1 Antibody (Catalog # M05882) . Tested in WB application (s) . This antibody reacts with Human.

Product Specifications

Background

Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Has broad substrate specificity and can use myo- inositol monophosphates, myo-inositol 1,3-diphosphate, myo- inositol 1,4-diphosphate, scyllo-inositol-phosphate, D-galactose 1-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1- phosphate, beta-glycerophosphate, and 2'-AMP as substrates.

Synonyms

Inositol monophosphatase 1, IMP 1, IMPase 1, 3.1.3.25, D-galactose 1-phosphate phosphatase, 3.1.3.94, Inositol-1 (or 4) -monophosphatase 1, Lithium-sensitive myo-inositol monophosphatase A1, IMPA1, IMPA

Gene Name

IMPA1

UniProt

P29218

Host

Mouse

Reactivity

Human

Immunogen

This IMPA1 antibody is generated from a mouse immunized with a recombinant protein from the human region of human IMPA1.

Clonality

Monoclonal

Clone

Clone: 2177CT172.34.52

Applications

WB

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Has broad substrate specificity and can use myo-inositol monophosphates, myo-inositol 1,3-diphosphate, myo-inositol 1,4- diphosphate, scyllo-inositol-phosphate, D-galactose 1-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta- glycerophosphate, and 2'-AMP as substrates.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

30189 Da

Applications Notes

WB: 1:1000-1:2000

Subcellular Location

Cytoplasm.

Prediction Reactivity

Human

Isotype

IgG1, κ

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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