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Anti-SYP Antibody (C-term)

Boster Bio Anti-SYP Antibody (C-term) (Catalog # M05049-4) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

Product Specifications

Background

Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity) .

Synonyms

Synaptophysin, Major synaptic vesicle protein p38, SYP

Gene Name

SYP

UniProt

P08247

Host

Mouse

Reactivity

Human, Mouse

Immunogen

This SYP antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 220-253 amino acids from the C-terminal region of human SYP.

Clonality

Monoclonal

Clone

Clone: 701CT23.9.8

Tissue Specificity

Expressed in the brain, with expression in the hippocampus, the neuropil in the dentate gyrus, where expression is higher in the outer half of the molecular layer than in the inner half, and in the neuropil of CA4 and CA3 (PubMed:8838578) . Expressed in the putamen (at protein level) (PubMed:17296554)

Applications

WB

Field of Research

Neuroscience

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity) .

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

33845 Da

Applications Notes

WB: 1:4000

Subcellular Location

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Synapse, synaptosome

Prediction Reactivity

Rat

Isotype

IgG1, k

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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