Anti-STMN2 Antibody (Center)
Boster Bio Anti-STMN2 Antibody (Center) (Catalog # M04729) . Tested in WB, IHC, IF, Flow Cytometry application (s) . This antibody reacts with Human, Mouse.
Product Specifications
Background
Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone (By similarity) .
Synonyms
Stathmin-2, Superior cervical ganglion-10 protein, Protein SCG10, STMN2, SCG10, SCGN10
Gene Name
STMN2
UniProt
Q93045
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This STMN2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 82-116 amino acids from the Central region of human STMN2.
Clonality
Polyclonal
Tissue Specificity
Neuron specific.
Applications
WB, IHC, IF, Flow Cytometry
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone (By similarity) .
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
20828 Da
Subcellular Location
Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone. Membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, axon. Golgi apparatus. Endosome. Cell projection, lamellipodium. Note=Associated with punctate structures in the perinuclear cytoplasm, axons, and growth cones of developing neurons. SCG10 exists in both soluble and membrane- bound forms. Colocalized with CIB1 in neurites of developing hippocampal primary neurons (By similarity) . Colocalized with CIB1 in the cell body, neuritis and growth cones of neurons. Colocalized with CIB1 to the leading edge of lamellipodia.
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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