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Anti-MYBBP1A Antibody

Boster Bio Anti-MYBBP1A Antibody (Catalog # M04187-1) . Tested in WB application (s) . This antibody reacts with Human.

Product Specifications

Background

May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity) . Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2. Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter.

Synonyms

Myb-binding protein 1A, MYBBP1A, P160

Gene Name

MYBBP1A

UniProt

Q9BQG0

Host

Mouse

Reactivity

Human

Immunogen

This MYBBP1A antibody is generated from a mouse immunized with a recombinant protein between 1104-1328 amino acids from human MYBBP1A.

Clonality

Monoclonal

Clone

Clone: 1702CT711.87.46

Applications

WB

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

29065309

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

148855 Da

Applications Notes

WB: 1:5000

Subcellular Location

Cytoplasm. Nucleus. Nucleus, nucleolus. Note=Shuttles between the nucleus and cytoplasm. Nuclear import may be mediated by KPNA2, while export appears to depend partially on XPO1/CRM1 (By similarity) . Predominantly nucleolar. {ECO:0000250|UniProtKB:Q7TPV4}

Isotype

IgG1, k

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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