Eupalinolide K
Product Specifications
UNSPSC Description
Eupalinolide K, a sesquiterpene lactones compound from Eupatorium lindleyanum, is a STAT3 inhibitor. Eupalinolide K is a Michael reaction acceptor (MRA) [1].
Target Antigen
STAT
Type
Natural Products
Related Pathways
JAK/STAT Signaling;Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/eupalinolide-k.html
Purity
99.20
Solubility
DMSO : 50 mg/mL (ultrasonic)|H2O : 5 mg/mL (ultrasonic)
Smiles
O=C(/C(C)=C/CO)O[C@H](C/C(C)=C\C[C@H](O)/C(C)=C\1)[C@](C2=C)([H])[C@]1([H])OC2=O
Molecular Weight
362.42
References & Citations
[1]Yang B, , et al. Precise discovery of a STAT3 inhibitor from <i>Eupatorium lindleyanum</i> and evaluation of its activity of anti-triple-negative breast cancer. Nat Prod Res. 2019 Feb;33(4):477-485.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N2240/Eupalinolide-K-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N2240/Eupalinolide-K-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
108657-10-9
Available Sizes
Curated Selection
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