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Anti-Rak FRK Monoclonal Antibody

Boster Bio Anti-Rak FRK Monoclonal Antibody catalog # M04075. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human.

Product Specifications

Synonyms

Tyrosine-protein kinase FRK;2.7.10.2; FYN-related kinase; Nuclear tyrosine protein kinase RAK; Protein-tyrosine kinase 5; FRK; PTK5, RAK

Gene Name

FRK

UniProt

P42685

Host

Mouse

Reactivity

Human

Immunogen

Purified recombinant fragment of Rak (aa2-300) expressed in E. Coli.

Clonality

Monoclonal

Clone

Clone: 1A8H2C12

Tissue Specificity

Predominantly expressed in epithelial derived cell lines and tissues, especially normal liver, kidney, breast and colon.

Applications

WB, IHC, IF, ELISA

Purification

Affinity purification

Concentration

1 mg/mL

Form

Liquid

Function

Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

58254 MW

Gene Name Synonym

Tyrosine-protein kinase FRK

Subcellular Location

Cytoplasm

Protein Name

Tyrosine-protein kinase FRK

Isotype

IgG

Contents

Ascitic fluid containing 0.03% sodium azide.

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