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Anti-PRKAR2A Antibody (C-Term)

Boster Bio Anti-PRKAR2A Antibody (C-Term) (Catalog # M03911-1) . Tested in WB application (s) . This antibody reacts with Human.

Product Specifications

Background

Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.

Synonyms

CAMP-dependent protein kinase type II-alpha regulatory subunit, PRKAR2A, PKR2, PRKAR2

Gene Name

PRKAR2A

UniProt

P13861

Host

Rabbit

Reactivity

Human

Immunogen

This PRKAR2A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 312-346 amino acids from the human region of human PRKAR2A.

Clonality

Polyclonal

Tissue Specificity

Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible

Applications

WB

Field of Research

Cancer, Metabolism, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

45518 Da

Applications Notes

WB: 1:2000

Subcellular Location

Cytoplasm. Cell membrane. Note=Colocalizes with PJA2 in the cytoplasm and the cell membrane

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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