Anti-TXNRD2 monoclonal Antibody
Boster Bio Anti-TXNRD2 monoclonal Antibody catalog # M03900. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Thioredoxin reductase 2, mitochondrial;1.8.1.9; Selenoprotein Z; SelZ; TR-beta; Thioredoxin reductase TR3; TXNRD2; KIAA1652, TRXR2
Gene Name
TXNRD2
UniProt
Q9NNW7
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full length Human TXNRD2.
Clonality
Monoclonal
Tissue Specificity
Highly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes. According to PubMed:10608886, high levels in kidney, whereas according to PubMed:9923614, levels are low. High expression is observed in the adrenal cortex (PubMed:24601690) .
Applications
WB
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis (PubMed:24601690) . Maintains thioredoxin in a reduced state. May play a role in redox-regulated cell signaling.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
56507 MW
Applications Notes
WB: 1:1000
Gene Name Synonym
Thioredoxin reductase 2, mitochondrial
Subcellular Location
Mitochondrion
Protein Name
Thioredoxin reductase 2, mitochondrial
Contents
1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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