Anti-PR3 PRTN3 Monoclonal Antibody
Boster Bio Anti-PR3 PRTN3 Monoclonal Antibody catalog # M03863. Tested in WB, ELISA applications. This antibody reacts with Human.
Product Specifications
Synonyms
Myeloblastin;3.4.21.76
Gene Name
PRTN3
UniProt
P24158
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant fragment of human PR3 expressed in E. Coli.
Clonality
Monoclonal
Clone
Clone: 3B4
Tissue Specificity
Expressed in polymorphonuclear leukocytes (at protein level) (PubMed:2033050, PubMed:7897245, PubMed:3198760) . Expressed in neutrophils (at protein level) (PubMed:28240246, PubMed:18462208, PubMed:21193407, PubMed:22266279, PubMed:17244676) . Expressed in differentiating neutrophils (PubMed:18462208) .
Applications
WB, ELISA
Purification
Affinity purification
Concentration
1 mg/mL
Form
Liquid
Function
Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246) . By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369) . May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
27807 MW
Gene Name Synonym
Myeloblastin
Subcellular Location
Cytoplasmic granule
Protein Name
Myeloblastin
Isotype
IgG
Contents
Ascitic fluid containing 0.03% sodium azide.
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