Anti-MAML2 Antibody (Center)
Boster Bio Anti-MAML2 Antibody (Center) (Catalog # M03679-1) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.
Product Specifications
Background
Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Potentiates activation by NOTCH3 and NOTCH4 more efficiently than MAML1 or MAML3.
Synonyms
Mastermind-like protein 2, Mam-2, MAML2, KIAA1819
Gene Name
MAML2
UniProt
Q8IZL2
Host
Rabbit
Reactivity
Human
Immunogen
This MAML2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 780-814 amino acids from the Central region of human MAML2.
Clonality
Polyclonal
Tissue Specificity
Widely expressed with high levels detected in placenta, salivary gland and skeletal muscle
Applications
WB, IHC-P
Field of Research
Stem Cells
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Potentiates activation by NOTCH3 and NOTCH4 more efficiently than MAML1 or MAML3.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
125197 Da
Subcellular Location
Nucleus speckle. Note=Nuclear, in a punctate manner
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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