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Anti-MAML2 Antibody (Center)

Boster Bio Anti-MAML2 Antibody (Center) (Catalog # M03679-1) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

Product Specifications

Background

Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Potentiates activation by NOTCH3 and NOTCH4 more efficiently than MAML1 or MAML3.

Synonyms

Mastermind-like protein 2, Mam-2, MAML2, KIAA1819

Gene Name

MAML2

UniProt

Q8IZL2

Host

Rabbit

Reactivity

Human

Immunogen

This MAML2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 780-814 amino acids from the Central region of human MAML2.

Clonality

Polyclonal

Tissue Specificity

Widely expressed with high levels detected in placenta, salivary gland and skeletal muscle

Applications

WB, IHC-P

Field of Research

Stem Cells

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Potentiates activation by NOTCH3 and NOTCH4 more efficiently than MAML1 or MAML3.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

125197 Da

Subcellular Location

Nucleus speckle. Note=Nuclear, in a punctate manner

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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