Anti-Natriuretic Peptide Receptor C Antibody
Boster Bio Anti-Natriuretic Peptide Receptor C Antibody (Catalog # M03589-1) . Tested in WB application (s) . This antibody reacts with Human.
Product Specifications
Background
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.
Synonyms
Atrial natriuretic peptide receptor 3, Atrial natriuretic peptide clearance receptor, Atrial natriuretic peptide receptor type C, ANP-C, ANPR-C, NPR-C, NPR3, ANPRC, C5orf23, NPRC
Gene Name
NPR3
UniProt
P17342
Host
Mouse
Reactivity
Human
Immunogen
This Natriuretic Peptide Receptor C antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 200-420 amino acids from the human region of human Natriuretic Peptide Receptor C.
Clonality
Monoclonal
Clone
Clone: 1748CT403.18.42
Applications
WB
Field of Research
Cardiovascular, Signal Transduction
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Function
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
59808 Da
Applications Notes
WB: 1:2000
Subcellular Location
Cell membrane; Single-pass type I membrane protein
Isotype
IgG1, k
Contents
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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