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Anti-Cripto TDGF1 Monoclonal Antibody

Boster Bio Anti-Cripto TDGF1 Monoclonal Antibody catalog # M03105. Tested in WB, ELISA applications. This antibody reacts with Human.

Product Specifications

Synonyms

Teratocarcinoma-derived growth factor 1; Cripto-1 growth factor; CRGF; Epidermal growth factor-like cripto protein CR1; TDGF1; CRIPTO

Gene Name

TDGF1

UniProt

P13385

Host

Mouse

Reactivity

Human

Immunogen

Purified recombinant fragment of human Cripto expressed in E. Coli.

Clonality

Monoclonal

Clone

Clone: 3A6

Tissue Specificity

Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts. Expressed in breast and lung.

Applications

WB, ELISA

Purification

Affinity purification

Concentration

1 mg/mL

Form

Liquid

Function

GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated TDGF1 acts as a Nodal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells (PubMed:27881714) . Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm (PubMed:11909953) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

21169 MW

Gene Name Synonym

Teratocarcinoma-derived growth factor 1

Subcellular Location

Cell membrane

Protein Name

Teratocarcinoma-derived growth factor 1

Isotype

IgG

Contents

Ascitic fluid containing 0.03% sodium azide.

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