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Anti-ACOX1 Antibody

Boster Bio Anti-ACOX1 Antibody (Catalog # M03054) . Tested in IF, IHC-P, WB application (s) . This antibody reacts with Human.

Product Specifications

Background

ACOX1 is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids.

Synonyms

Peroxisomal acyl-coenzyme A oxidase 1, AOX, Palmitoyl-CoA oxidase, Straight-chain acyl-CoA oxidase, SCOX, ACOX1, ACOX

Gene Name

ACOX1

UniProt

Q15067

Host

Mouse

Reactivity

Human

Immunogen

This ACOX1 monoclonal antibody is generated from mouse immunized with ACOX1 recombinant protein.

Clonality

Monoclonal

Clone

Clone: 153CT43.1.1

Tissue Specificity

Widely expressed with highest levels of isoform 1 and isoform 2 detected in testis. Isoform 1 is expressed at higher levels than isoform 2 in liver and kidney while isoform 2 levels are higher in brain, lung, muscle, white adipose tissue and testis. Levels are almost equal in heart.

Applications

IF, IHC-P, WB

Field of Research

Cancer, Cardiovascular, Metabolism, Signal Transduction

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

7876265150600851745887217603022321691713323438278762651745887217603022

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

74424 Da

Subcellular Location

Peroxisome.

Isotype

IgG1

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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