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Anti-ERK 3 MAPK6 Monoclonal Antibody

Boster Bio Anti-ERK 3 MAPK6 Monoclonal Antibody catalog # M03011. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human.

Product Specifications

Synonyms

Mitogen-activated protein kinase 6; MAP kinase 6; MAPK 6;2.7.11.24; Extracellular signal-regulated kinase 3; ERK-3; MAP kinase isoform p97; p97-MAPK; MAPK6; ERK3, PRKM6

Gene Name

MAPK6

UniProt

Q16659

Host

Mouse

Reactivity

Human

Immunogen

Purified recombinant fragment of human ERK 3 expressed in E. Coli.

Clonality

Monoclonal

Clone

Clone: 400000000

Tissue Specificity

Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.

Applications

WB, Flow Cytometry, ELISA

Purification

Affinity purification

Concentration

1 mg/mL

Form

Liquid

Function

Atypical MAPK protein. Phosphorylates microtubule- associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

82681 MW

Gene Name Synonym

Mitogen-activated protein kinase 6

Subcellular Location

Cytoplasm . Nucleus . Translocates to the cytoplasm following interaction with MAPKAPK5. .

Protein Name

Mitogen-activated protein kinase 6

Isotype

IgG

Contents

Ascitic fluid containing 0.03% sodium azide.

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