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Anti-CBR1 monoclonal Antibody

Boster Bio Anti-CBR1 monoclonal Antibody catalog # M02825. Tested in WB, ICC applications. This antibody reacts with Human.

Product Specifications

Synonyms

Carbonyl reductase [NADPH] 1;1.1.1.184;15-hydroxyprostaglandin dehydrogenase [NADP (+) ];1.1.1.197; NADPH-dependent carbonyl reductase 1; Prostaglandin 9-ketoreductase; Prostaglandin-E (2) 9-reductase;1.1.1.189; Short chain dehydrogenase/reductase family 21C member 1; CBR1; CBR, CRN, SDR21C1

Gene Name

CBR1

UniProt

P16152

Host

Mouse

Reactivity

Human

Immunogen

Recombinant full length Human CBR1.

Clonality

Monoclonal

Applications

WB, ICC

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

30375 MW

Gene Name Synonym

Carbonyl reductase [NADPH] 1

Subcellular Location

Cytoplasm.

Protein Name

Carbonyl reductase [NADPH] 1

Contents

1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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