Anti-CBR1 monoclonal Antibody
Boster Bio Anti-CBR1 monoclonal Antibody catalog # M02825. Tested in WB, ICC applications. This antibody reacts with Human.
Product Specifications
Synonyms
Carbonyl reductase [NADPH] 1;1.1.1.184;15-hydroxyprostaglandin dehydrogenase [NADP (+) ];1.1.1.197; NADPH-dependent carbonyl reductase 1; Prostaglandin 9-ketoreductase; Prostaglandin-E (2) 9-reductase;1.1.1.189; Short chain dehydrogenase/reductase family 21C member 1; CBR1; CBR, CRN, SDR21C1
Gene Name
CBR1
UniProt
P16152
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full length Human CBR1.
Clonality
Monoclonal
Applications
WB, ICC
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
30375 MW
Gene Name Synonym
Carbonyl reductase [NADPH] 1
Subcellular Location
Cytoplasm.
Protein Name
Carbonyl reductase [NADPH] 1
Contents
1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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