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Anti-MCM3 Antibody

Boster Bio Anti-MCM3 Antibody (Catalog # M02580-1) . Tested in WB, Flow Cytometry application (s) . This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation.

Synonyms

DNA replication licensing factor MCM3, DNA polymerase alpha holoenzyme-associated protein P1, P1-MCM3, RLF subunit beta, p102, MCM3

Gene Name

MCM3

UniProt

P25205

Host

Mouse

Reactivity

Human, Mouse, Rat

Immunogen

This MCM3 antibody is generated from a mouse immunized with a recombinant protein of human MCM3.

Clonality

Monoclonal

Clone

Clone: 1593CT377.41.73

Applications

WB, Flow Cytometry

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

3245342534694004347003283558523232453425

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

90981 Da

Subcellular Location

Nucleus. Chromosome. Note=Associated with chromatin before the formation of nuclei and detaches from it as DNA replication progresses.

Isotype

IgG1, k

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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