Anti-Crk2 monoclonal Antibody
Boster Bio Anti-Crk2 monoclonal Antibody catalog # M02533. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Adapter molecule crk; Proto-oncogene c-Crk; p38; CRK
Gene Name
CRK
UniProt
P46108
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full length Human Crk2.
Clonality
Monoclonal
Applications
WB
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Isoform Crk-II: Regulates cell adhesion, spreading and migration. Mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
33831 MW
Applications Notes
WB: 1:1000
Gene Name Synonym
Adapter molecule crk
Subcellular Location
Cytoplasm . Cell membrane . Translocated to the plasma membrane upon cell adhesion. .
Protein Name
Adapter molecule crk
Contents
1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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