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Anti-Trk C NTRK3 Monoclonal Antibody

Boster Bio Anti-Trk C NTRK3 Monoclonal Antibody catalog # M02502. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human.

Product Specifications

Synonyms

NT-3 growth factor receptor;2.7.10.1; GP145-TrkC; Trk-C; Neurotrophic tyrosine kinase receptor type 3; TrkC tyrosine kinase; NTRK3; TRKC

Gene Name

NTRK3

UniProt

Q16288

Host

Mouse

Reactivity

Human

Immunogen

Purified recombinant extracellular fragment of human Trk C (aa32-429) fused with hIgGFc tag expressed in HEK293 cells.

Clonality

Monoclonal

Clone

Clone: 7H6

Tissue Specificity

Widely expressed but mainly in nervous tissue. Isoform 2 is expressed at higher levels in adult brain than in fetal brain.

Applications

WB, IHC, IF, ELISA

Purification

Affinity purification

Concentration

1 mg/mL

Form

Liquid

Function

Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

94428 MW

Gene Name Synonym

NT-3 growth factor receptor

Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Name

NT-3 growth factor receptor

Isotype

IgG

Contents

Ascitic fluid containing 0.03% sodium azide.

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