Anti-Fibulin-5 FBLN5 Monoclonal Antibody
Boster Bio Anti-Fibulin-5 FBLN5 Monoclonal Antibody catalog # M02317. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human.
Product Specifications
Synonyms
Fibulin-5; FIBL-5; Developmental arteries and neural crest EGF-like protein; Dance; Urine p50 protein; UP50; FBLN5; DANCE; UNQ184/PRO210
Gene Name
FBLN5
UniProt
Q9UBX5
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant fragment of Fibulin-5 expressed in E. Coli.
Clonality
Monoclonal
Clone
Clone: 3F10A5 / 3F8A12
Tissue Specificity
Expressed in skin fibroblasts (at protein level) (PubMed:17035250) . Expressed predominantly in heart, ovary, and colon but also in kidney, pancreas, testis, lung and placenta. Not detectable in brain, liver, thymus, prostate, or peripheral blood leukocytes (PubMed:10428823) .
Applications
WB, IHC, IF, ELISA
Purification
Affinity purification
Concentration
1 mg/mL
Form
Liquid
Function
Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN (PubMed:18185537) . Stabilizes and organizes elastic fibers in the skin, lung and vasculature (By similarity) . Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling (PubMed:10428823) . May act as an adapter that mediates the interaction between FBN1 and ELN (PubMed:17255108) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
50180 MW
Gene Name Synonym
Fibulin-5
Subcellular Location
Secreted
Protein Name
Fibulin-5
Isotype
IgG
Contents
Ascitic fluid containing 0.03% sodium azide.
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