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Anti-CHRNA4 Antibody (N-Term)

Boster Bio Anti-CHRNA4 Antibody (N-Term) (Catalog # M02230) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

Product Specifications

Background

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions.

Synonyms

Neuronal acetylcholine receptor subunit alpha-4, CHRNA4, NACRA4

Gene Name

CHRNA4

UniProt

P43681

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This CHRNA4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 176-208 amino acids from human CHRNA4.

Clonality

Polyclonal

Applications

WB

Field of Research

Cancer, Metabolism, Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

69957 Da

Applications Notes

WB: 1:2000

Subcellular Location

Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell membrane; Lipid-anchor

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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