Anti-CTBP1 Purified Rabbit Monoclonal Antibody
Boster Bio Anti-CTBP1 Purified Rabbit Monoclonal Antibody (Catalog# M02123) . Tested in IP, WB, ICC application (s) . This antibody reacts with Mouse, Human.
Product Specifications
Background
C-terminal binding protein 1 / brefeldin A (BFA) -dependent ADP-ribosylation substrate (CtBP1/BARS) is a highly conserved transcriptional corepressor, that plays a critical role in regulating gene expression patterns throughout development and in oncogenesis. CtBP regulates target gene transcription, in part, via recruitment of histone deacetylases involved in gene silencing and may act to coordinate histone modifications that regulate gene expression.
Synonyms
BARS, HADDTS
Gene Name
CTBP1
UniProt
Q13363
Host
Rabbit
Reactivity
Mouse, Human
Immunogen
Bacterially expressed full-length human CtBP1. The polyclonal antibody reacts with CtBP1, a 49 kDa transcriptional corepressor (intracellular antigen), that plays a critical role in regulating gene expression.
Clonality
Monoclonal
Clone
Clone: PAb (511)
Tissue Specificity
Expressed in germinal center B-cells.
Applications
IP, WB, ICC
Purification
Purified by ligand affinity chromatography.
Concentration
1 mg/mL
Form
Liquid
Function
Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation.
Storage Conditions
Store at 2-8°C. Do not freeze.
Observed Molecular Weight
47535 MW
Gene Name Synonym
C-terminal binding protein 1
Subcellular Location
Cytoplasm
Protein Name
C-terminal-binding protein 1
Isotype
Rabbit polyclonal
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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