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Anti-KRT19 Antibody

Boster Bio Anti-KRT19 Antibody (Catalog # M02101-5) . Tested in IHC-P, IF, WB application (s) . This antibody reacts with Human.

Product Specifications

Background

Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.

Synonyms

Keratin, type I cytoskeletal 19, Cytokeratin-19, CK-19, Keratin-19, K19, KRT19

Gene Name

KRT19

UniProt

P08727

Host

Mouse

Reactivity

Human

Immunogen

This antibody is generated from a mouse immunized with a recombinant protein of human.

Clonality

Monoclonal

Clone

Clone: 979CT14.3.1

Tissue Specificity

Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level) . Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin.

Applications

IHC-P, IF, WB

Field of Research

Signal Transduction, Viral process, Host-Virus Interaction

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

44106 Da

Isotype

IgG1, k

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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