Anti-Ataxin-1 ATXN1 Monoclonal Antibody
Boster Bio Anti-Ataxin-1 ATXN1 Monoclonal Antibody catalog # M01786. Tested in WB, IHC, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human.
Product Specifications
Synonyms
Ataxin-1; Spinocerebellar ataxia type 1 protein; ATXN1; ATX1, SCA1
Gene Name
ATXN1
UniProt
P54253
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant fragment of human Ataxin-1 expressed in E. Coli.
Clonality
Monoclonal
Clone
Clone: 2F5
Tissue Specificity
Widely expressed throughout the body.
Applications
WB, IHC, IF, Flow Cytometry, ELISA
Purification
Affinity purification
Concentration
1 mg/mL
Form
Liquid
Function
Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism (PubMed:21475249) . In concert with CIC and ATXN1L, involved in brain development (By similarity) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
86923 MW
Gene Name Synonym
Ataxin-1
Subcellular Location
Cytoplasm
Protein Name
Ataxin-1
Isotype
IgG
Contents
Ascitic fluid containing 0.03% sodium azide.
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