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Anti-NDC80 Antibody (C-Term)

Boster Bio Anti-NDC80 Antibody (C-Term) (Catalog # M01731-1) . Tested in WB application (s) . This antibody reacts with Human.

Product Specifications

Background

Acts as a component of the essential kinetochore- associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.

Synonyms

Kinetochore protein NDC80 homolog, Highly expressed in cancer protein, Kinetochore protein Hec1, HsHec1, Kinetochore-associated protein 2, Retinoblastoma-associated protein HEC, NDC80, HEC, HEC1, KNTC2

Gene Name

NDC80

UniProt

O14777

Host

Rabbit

Reactivity

Human

Immunogen

This NDC80 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 594-628 amino acids from human NDC80.

Clonality

Polyclonal

Applications

WB

Field of Research

Cancer, Cell Biology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

93156641235179014654001146991291506210315235793152399531554859216732327304099121554859230409912230850202574320523891108

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

73913 Da

Applications Notes

WB: 1:2000

Subcellular Location

Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late prophase to anaphase (PubMed:14699129) Localizes specifically to the outer plate of the kinetochore (PubMed:14699129) .

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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