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Anti-RAC2 Antibody (C-term)

Boster Bio Anti-RAC2 Antibody (C-term) (Catalog # M01714) . Tested in WB, IF application (s) . This antibody reacts with Human, Mouse.

Product Specifications

Background

Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.

Synonyms

Ras-related C3 botulinum toxin substrate 2, GX, Small G protein, p21-Rac2, RAC2

Gene Name

RAC2

UniProt

P15153

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This RAC2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 178-192 amino acids from the C-terminal region of human RAC2.

Clonality

Polyclonal

Tissue Specificity

Hematopoietic specific.

Applications

WB, IF

Field of Research

Anti-Wnt-Pathway (plus Lgr5) Antibodies, Immunology, T Cells, Chemokine signaling, Inflammation

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

21429 Da

Subcellular Location

Cytoplasm. Note=Membrane-associated when activated

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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