Anti-DNM2 Antibody (N-Term)

Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity) . Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis.

Cytoplasm. Cytoplasm, cytoskeleton. Cell junction {ECO:0000250|UniProtKB:P39052}. Membrane, clathrin-coated pit {ECO:0000250|UniProtKB:P39052}. Postsynaptic density. Synapse. Midbody Cell projection, phagocytic cup {ECO:0000250|UniProtKB:P39054} Cytoplasmic vesicle, phagosome membrane {ECO:0000250|UniProtKB:P39054}; Peripheral membrane protein {ECO:0000250|UniProtKB:P39054} Note=Colocalizes with CTTN at the basis of filopodia in hippocampus neuron growth zones (By similarity) . Microtubule-associated. Also found in the postsynaptic density of neuronal cells. Co-localizes with PIK3C3 and RAB5A to the nascent phagosome (By similarity) {ECO:0000250|UniProtKB:P39052, ECO:0000250|UniProtKB:P39054}