Anti-DNM2 Antibody (N-Term)

Boster Bio Anti-DNM2 Antibody (N-Term) (Catalog # M01629-1) . Tested in WB, Flow Cytometry, IF application (s) . This antibody reacts with Human, Mouse.

Product Specifications

Background

Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity) . Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis.

Synonyms

Dynamin-2, 3.6.5.5, DNM2, DYN2

Gene Name

DNM2

UniProt

P50570

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This DNM2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 213-247 amino acids from human DNM2.

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed.

Applications

WB, Flow Cytometry, IF

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

3371362012498685

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

98064 Da

Subcellular Location

Cytoplasm. Cytoplasm, cytoskeleton. Cell junction {ECO:0000250|UniProtKB:P39052}. Membrane, clathrin-coated pit {ECO:0000250|UniProtKB:P39052}. Postsynaptic density. Synapse. Midbody Cell projection, phagocytic cup {ECO:0000250|UniProtKB:P39054} Cytoplasmic vesicle, phagosome membrane {ECO:0000250|UniProtKB:P39054}; Peripheral membrane protein {ECO:0000250|UniProtKB:P39054} Note=Colocalizes with CTTN at the basis of filopodia in hippocampus neuron growth zones (By similarity) . Microtubule-associated. Also found in the postsynaptic density of neuronal cells. Co-localizes with PIK3C3 and RAB5A to the nascent phagosome (By similarity) {ECO:0000250|UniProtKB:P39052, ECO:0000250|UniProtKB:P39054}