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Anti-BCL10 Antibody

Boster Bio Anti-BCL10 Antibody (Catalog # M01616) . Tested in IHC-P, Flow Cytometry, WB application (s) . This antibody reacts with Human.

Product Specifications

Background

Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1.

Synonyms

B-cell lymphoma/leukemia 10, B-cell CLL/lymphoma 10, Bcl-10, CARD-containing molecule enhancing NF-kappa-B, CARD-like apoptotic protein, hCLAP, CED-3/ICH-1 prodomain homologous E10-like regulator, CIPER, Cellular homolog of vCARMEN, cCARMEN, Cellular-E10, c-E10, Mammalian CARD-containing adapter molecule E10, mE10, BCL10, CIPER, CLAP

Gene Name

BCL10

UniProt

O95999

Host

Mouse

Reactivity

Human

Immunogen

This BCL10 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 1-143 amino acids from the human region of human BCL10.

Clonality

Monoclonal

Clone

Clone: 1185CT13.2.1.2

Tissue Specificity

Ubiquitous.

Applications

IHC-P, Flow Cytometry, WB

Field of Research

Cancer, Cell Biology, Metabolism, Signal Transduction, Immunology, T Cells

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

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Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

26252 Da

Subcellular Location

Cytoplasm, perinuclear region. Membrane raft. Note=Appears to have a perinuclear, compact and filamentous pattern of expression. Also found in the nucleus of several types of tumor cells. Colocalized with DPP4 in membrane rafts.

Isotype

IgG1, κ

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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