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Anti-MAP1LC3A antibody (N-term)

Boster Bio Anti-MAP1LC3A antibody (N-term) (Catalog # M01543-2) . Tested in IHC-P-Leica, WB application (s) . This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) . Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.

Synonyms

Microtubule-associated proteins 1A/1B light chain 3A, Autophagy-related protein LC3 A, Autophagy-related ubiquitin-like modifier LC3 A, MAP1 light chain 3-like protein 1, MAP1A/MAP1B light chain 3 A, MAP1A/MAP1B LC3 A, Microtubule-associated protein 1 light chain 3 alpha, MAP1LC3A

Gene Name

MAP1LC3A

UniProt

Q9H492

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1-40 amino acids from human.

Clonality

Polyclonal

Tissue Specificity

Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes

Applications

IHC-P-Leica, WB

Field of Research

Cancer, Cardiovascular, Cell Biology, Metabolism, Microbiology, Neuroscience, Signal Transduction, Autophagy

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

2071360024290141207136003100653831006537

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

14272 Da

Subcellular Location

Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Endomembrane system; Lipid-anchor. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q91VR7}. Note=LC3-II binds to the autophagic membranes.

Prediction Reactivity

Zebrafish, Bovine

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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